منابع مشابه
Systemic Therapy for Invasive Bladder Cancer.
BACKGROUND: Bladder cancer is one of the most common malignancies in Western society. In the United States, approximately 10,000 of these patients present with invasive disease, and more progress from superficial bladder cancer. METHODS: The authors review the literature on systemic treatment for both localized and metastatic bladder cancer, and they include their experience in defining approac...
متن کاملSystemic Therapy for Invasive Bladder Cancer: The Value Proposition
The report from Yin et al. in this issue of The Oncologist is an important reminder of the utility of neoadjuvant cisplatinbased chemotherapy for invasive, clinically nonmetastatic bladder cancer [1]. In their updated analysis, these investigators suggest that the hazard ratio from this treatment strategy has improved to 0.87, from approximately 0.93; the analysis now includesmore than 3,000 ca...
متن کاملSystemic therapy for bladder cancer - a medical oncologist's perspective.
Advanced bladder cancer, both muscle-invasive localized disease and metastatic disease, is managed with systemic chemotherapy. Cisplatin-based multi-agent chemotherapy remains the cornerstone for systemic therapy. MVAC (methotrexate-vinblastine-doxorubicin-cisplatin) has been most rigorously studied, both neoadjuvantly and for palliation of metastatic disease. For metastatic disease, cisplatin-...
متن کاملRole of MicroRNAs in BCG Therapy by the Induction of Neutrophil Extracellular Traps in Bladder Cancer
The treatment of bladder cancer is usually performed by Bacillus Calmette-Guerin (BCG) instillation. BCG therapy is a common therapeutic method with fewer side effects compared with chemotherapy, radiotherapy, etc. BCG can also inhibit the progression and recurrence of bladder cancer by inducing apoptosis pathways, arrest cell cycle, autophagy, and neutrophil extracellular traps (NETs) formatio...
متن کاملIntravesical therapy in superficial bladder cancer.
OBJECTIVE To identify the appropriate characteristics of superficial bladder cancer that allow the physician to predict tumor behavior. METHODS We analyzed 1,745 patients with primary superficial bladder cancer with regard to disease and patient characteristics. RESULTS With the characteristics we found, the population can be described and prognostic factors can be found. Moreover, with the...
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ژورنال
عنوان ژورنال: Indian Journal of Urology
سال: 2017
ISSN: 0970-1591
DOI: 10.4103/iju.iju_294_16